Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| LVMBS9 | LVMBS9 | DRC | 1997 | HIV1 | A | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, G16E, K20I, E35D, M36I, R41K, I64M, H69K, K70R, L89M |
| >LVMBS9| codons 1-99 PQITLWQRPLVTVRIEGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILMEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39A, D121H, K122E, D123E, I135V, A158S, K173T, Q174K, D177E, T200A, Q207D, R211K, V245Q, E248N, S251C, R284K, T286A, E291D, V292I, I293V, P294T, E312D, G335D, R356K, M357K, G359S, K366R, A371V, I375V, K390R, K395R, T403M |
| >LVMBS9| codons 1-421 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HEEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRTKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRDHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPNKDCWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLKGAKALTDIVTLTEEAE LELAENREILKDPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA HTNDVRQLTEVVQKVATESIVIWGKTPKFRLPIQRETWEAWWMEYWQATWIPEWEFVNTP P |
References
| Author | Title | Citation |
| Vergne, L | Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: evidence of many minor drug resistance mutations in treatment-naive patients. | J Clin Microbiol, 2000 |