<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
LVMBTB54 LVMBTB54 DRC 1997 HIV1 A PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, L19T, K20I, E35D, M36I, R41K, H69K, L89M  
>LVMBTB54| codons 1-99
PQITLWQRPLVTVRIGGQTIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6D, K11T, V35T, K43R, K122E, D123S, K173L, D177E, T200A, Q207E, A272P, V276I, T286A, E291D, V292I, I293V, P294T, E312D, D324E, I326V, G335D, M357K, G359S, A371V, I375V, A376T, T377L, I393M, T403M, E413D  
>LVMBTB54| codons 1-421
PISPIDTVPVTLKPGMDGPKVKQWPLTEEKIKALTEICTEMEREGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRLQNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKIKQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKDPVHGVYYDPSKELVAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA
HTNDVKQLTEVVQKVTLESIVIWGKTPKFKLPMQKETWEAWWMEYWQATWIPDWEFVNTP
P

References
Author Title Citation
Vergne, L Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: evidence of many minor drug resistance mutations in treatment-naive patients. J Clin Microbiol, 2000