Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| LVMB92 | LVMBP2 | DRC | 1997 | HIV1 | CRF02_AG | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13A, K14R, K20I, E35D, M36I, N37D, R41K, K43R, H69K, K70R, L89M |
| >LVMBP2| codons 1-99 PQITLWQRPLVTARIGGQLIEALLDTGADDTVLEDIDLPGKWRPKMIGGIGGFIKVRQYD QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6K, K11Q, V35I, T39S, S48T, K122E, D123G, K166T, K173A, Q174E, D177E, I178M, T200A, Q207E, V245Q, E248D, S251N, A272P, K281R, T286A, E291D, V292I, I293V, P294T, K311R, E312D, D324E, Q334P, G335D, R356K, M357R, G359S, T362L, T369V, E370D, A371V, I375V, A376T, K390R, K395R, T403M, Y405H | Q182H |
| >LVMBP2| codons 1-421 PISPIKTVPVQLKPGMDGPKVKQWPLTEEKIKALIEICSEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTTILEPFRAENPEMVI YHYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDNWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDIVTLTEEAE LELAENREILRDPVHGVYYDPSKELIAEIQKQGPDQWTYQIYQEPFKNLKTGKYAKRRSA HLNDVKQLVDVVQKVTTESIVIWGKTPKFRLPIQRETWEAWWMEHWQATWIPEWEFVNTP P |
References
| Author | Title | Citation |
| Vergne, L | Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: evidence of many minor drug resistance mutations in treatment-naive patients. | J Clin Microbiol, 2000 |