Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| LVMBFE247 | LVMBFE247 | DRC | 1997 | HIV1 | CRF02_AG | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, K14R, K20I, M36I, R41K, L63N, I66V, H69K, L89M |
| >LVMBFE247| codons 1-99 PQITLWQRPIVTVRIGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QINIEVCGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V8I, V35T, C38V, K104R, K122E, D123S, I135T, K173A, Q174K, D177E, T200A, Q207E, V245Q, E248D, D250E, T286A, E291D, V292I, I293V, P294T, E312D, D324E, I326V, G335D, M357K, G359S, A371V, I375V, T377I, K390R, T403M | T39H |
| >LVMBFE247| codons 1-421 PISPIETIPVKLKPGMDGPKVKQWPLTEEKIKALTEIVHEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKDPVHGVYYDPSKELVAEIQKQGQDQWTYQIYQEPFKNLKTGKYARKRSA HTNDVKQLTEVVQKVAIESIVIWGKTPKFRLPIQKETWEAWWMEYWQATWIPEWEFVNTP P |
References
| Author | Title | Citation |
| Vergne, L | Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: evidence of many minor drug resistance mutations in treatment-naive patients. | J Clin Microbiol, 2000 |