Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| LV63HPD | LV63HPD | Senegal | 1999 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, K14R, K20I, E35D, M36I, R41K, L63P, C67E, H69K, V82I, L89M, I93V |
| >LV63HPD| codons 1-99 PQITLWQRPIVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIPIEIEGKKAIGTVLVGPTPINIIGRNMLTQVGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E40D, K49R, V60I, A98S, D123N, K173T, Q174K, D177E, T200A, Q207G, V245Q, D250E, A272P, K275Q, K281R, T286A, E291D, V292I, I293V, E297A, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, E370D, A371V, A376S, T377M, T386I, K390R, Q394R, A400V, E404D, E413D |
| >LV63HPD| codons 1-421 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DKNFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRGHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIQVKQLCRLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEVQKQGLDQWTYQIYQEPYKNLKTGKYAKRGSA HTNDVKQLTDVVQKISMESIVIWGKIPKFRLPIRKETWEVWWTDYWQATWIPDWEFVNTP P |
References
| Author | Title | Citation |
| Vergne, L | Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: evidence of many minor drug resistance mutations in treatment-naive patients. | J Clin Microbiol, 2000 |
| Diop-Ndiaye, H | Antiretroviral drug resistance mutations in antiretroviral-naive patients from Senegal. | ARHR, 2010 |