<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
LV64HALD LV64HALD Senegal 1999 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 None NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K20R, V35T, T39A, K49R, V60I, K104R, D121H, K122E, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, P243S, V245Q, E248N, D250E, V261I, A272S, T286A, E291D, V292I, I293V, E297A, G333E, Q334H, T338S, F346H, R358K, G359S, T386I, K390R, A400I, E404D  
>LV64HALD| codons 1-421
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICAEMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL
HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEMVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQSIQLPNKESWTVNDIQKLIGKLNWASQIYSGIKVKQLCKLLRGAKALTDIVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQEHGQWSYQIYQEPHKNLKTGKYARMKSA
HTNDVKQLTEAVQKIATESIVIWGKIPKFRLPIQKETWEIWWTDYWQATWIPEWEFVNTP
P

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, I15V, K20I, M36I, R41K, I64M, H69K, K70R, L89M  
>LV64HALD| codons 1-99
PQITLWQRPLVTVKVGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QILMEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Vergne, L Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: evidence of many minor drug resistance mutations in treatment-naive patients. J Clin Microbiol, 2000
Diop-Ndiaye, H Antiretroviral drug resistance mutations in antiretroviral-naive patients from Senegal. ARHR, 2010