Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| LV64HALD | LV64HALD | Senegal | 1999 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K20R, V35T, T39A, K49R, V60I, K104R, D121H, K122E, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, P243S, V245Q, E248N, D250E, V261I, A272S, T286A, E291D, V292I, I293V, E297A, G333E, Q334H, T338S, F346H, R358K, G359S, T386I, K390R, A400I, E404D |
| >LV64HALD| codons 1-421 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICAEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEMVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQSIQLPNKESWTVNDIQKLIGKLNWASQIYSGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQEHGQWSYQIYQEPHKNLKTGKYARMKSA HTNDVKQLTEAVQKIATESIVIWGKIPKFRLPIQKETWEIWWTDYWQATWIPEWEFVNTP P |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, I15V, K20I, M36I, R41K, I64M, H69K, K70R, L89M |
| >LV64HALD| codons 1-99 PQITLWQRPLVTVKVGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILMEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Vergne, L | Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: evidence of many minor drug resistance mutations in treatment-naive patients. | J Clin Microbiol, 2000 |
| Diop-Ndiaye, H | Antiretroviral drug resistance mutations in antiretroviral-naive patients from Senegal. | ARHR, 2010 |