Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| LV6 | LV6 | Cameroon | 1997 | HIV1 | CRF02_AG | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L33F | I13V, K14R, K20I, M36I, N37S, P39A, R41K, H69K, L89M |
| >LV6| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVFEEISLAGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36D, D123N, I135V, I142V, S162A, Q174N, D177E, T200A, Q207N, V245Q, K275R, K277R, T286A, E291D, V292I, I293V, P294T, V317A, S322T, G335D, R356K, M357K, R358K, G359S, A371V, I375V, K390R, K395R, T403M, E432D, V435A |
| >LV6| codons 1-436 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKNFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQASMTKILEPFRKNNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRNHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIRVRQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGAYYDPTKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKKSA HTNDVKQLTEVVQKVATESIVIWGKTPKFRLPIQRETWEAWWMEYWQATWIPEWEFVNTP PLVKLWYQLEKDPIAG |
References
| Author | Title | Citation |
| Vergne, L | Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: evidence of many minor drug resistance mutations in treatment-naive patients. | J Clin Microbiol, 2000 |