<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
LVMP634 LVMP634 Cameroon 1997 HIV1 D PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I15V, L19V, E35D, M36I, R41K, R57K, I62V, L63S, H69Q, K70Q, V77I  
>LVMP634| codons 1-99
PQITLWQRPVVTIKVGGQVKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QVSIEICGQQAIGTVLIGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        P4T, K11T, V35A, K49R, V118I, I135T, S162C, R172K, D177E, I178L, V179I, T200I, Q207N, R211K, F214L, V245T, E248D, D250E, A272P, T286A, E297K, K311R, I329V, Q334E, G335S, Y339W, G359S, K390R, T403R Q182S
>LVMP634| codons 1-421
PISTIETVPVTLKPGMDGPKVKQWPLTEEKIKALAEICTEMEKEGKISRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFKKQNPELII
YSYMDDLYVGSDLEIGQHRIKIEELRNHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPITLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTKEAE
LELAENREILREPVHGVYYDPSKDLIAEVQKQGESQWTWQIYQEPFKNLKTGKYARMRSA
HTNDVKQLTEAVQKIATESIVIWGKTPKFRLPIQKETWEAWWREYWQATWIPEWEFVNTP
P

References
Author Title Citation
Vergne, L Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: evidence of many minor drug resistance mutations in treatment-naive patients. J Clin Microbiol, 2000