Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PHPT4771 | PHPT4771PR-RT | Thailand | 2007 | HIV1 | CRF01_AE | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | EFV+FTC+TDF | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N | E6D, K11T, V35T, T39K, K43E, S68SG, K122E, D123S, K173I, Q174K, D177E, T200I, Q207A, R211N, K238R, V245E, T286TA, E291D, V292I, I293V, E312T, V317T, I326V, I329V |
| >PHPT4771PR-RT| codons 1-334 PISPIDTVPVTLKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEIVI YQYMDDLYVGSDLEIGQHRIKIEELRAHLLNWGFTTPDKKHQKEPPFLWMGYELHPDRWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKTPVHGTYYDPSKDLVAEVQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10N, K20KR, M36I, R41K, L63S, H69K, L89M |
| >PHPT4771PR-RT| codons 1-99 PQITLWQRPNVTIKIGGQLREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QISIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Ngo-Giang-Huong, N | Resistance patterns selected by nevirapine vs. efavirenz in HIV-infected patients failing first-line antiretroviral treatment: A bayesian analysis. | PLoS ONE, 2011 |
| Rhee, SY | Mutational Correlates of Virological Failure in Individuals Receiving a WHO-Recommended Tenofovir-Containing First-Line Regimen: An International Collaboration. | EBioMedicine, 2017 |