<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 EFV+FTC+TDF NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V V75M K103N   E6D, K11T, V35T, T39K, K43E, V111I, E138G, K173V, Q174K, D177E, I178L, V179IT, T200TI, I202V, Q207A, K238S, V245E, K249R, S251C, T286A, E291D, P294PQ, E312NT, I326V, I329V Y232H
>PHPT4163PR-RT| codons 1-334
PISPIDTVPVTLKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDIGDAYFSVPL
DKDFRKYTAFTIPSINNGTPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRVKNPELTI
YQYVDDLYVGSDLEIGQHRIKVEELRAHLLRWGFTTPDKKHQKEPPFLWMGHELHPDSWT
VQPIELPERDCWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDVIQLTEEAE
LELAENREILKTPVHGVYYDPSKDLVAEVQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, I15IV, K20KI, E35D, M36I, R41K, K43KR, R57RK, H69K, V82I, L89M, T91V  
>PHPT4163PR-RT| codons 1-99
PQITLWQRPLVTVKVGGQLIEALLDTGADDTVLEDINLPGKWRPKMIGGIGGFIKVKQYD
QILIEICGKKAIGTVLVGPTPINIIGRNMLVQIGCTLNF

References
Author Title Citation
Ngo-Giang-Huong, N Resistance patterns selected by nevirapine vs. efavirenz in HIV-infected patients failing first-line antiretroviral treatment: A bayesian analysis. PLoS ONE, 2011