<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K101E, G190A Y318F E6D, K11S, E28EK, V35T, T39K, K43E, S68G, K122E, D123N, I135T, K166R, K173I, Q174K, D177E, I178M, G196E, Q207A, R211S, K238R, I244V, V245E, A272P, K275R, V276I, T286A, E291D, V292I, I293V, E297G, E312T, I326V, I329V  
>PHPT1374PR-RT| codons 1-334
PISPIDTVPVSLKPGMDGPKVKQWPLTKEKIKALTEICKEMEEEGKISKIGPENPYNTPV
FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRIKNPEMVI
YQYVDDLYVASDLEIEQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDRWT
VQPVELPEKDSWTVNDIQKLVGKLNWASQIYPGIRIKQLCKLLRGAKALTDIVPLTGEAE
LELAENREILKTPVHGVFYDPSKDLVAEVQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10LV, T12TP, I13V, I15IV, K20R, E35D, M36I, R41K, R57K, H69K, L89M  
>PHPT1374PR-RT| codons 1-99
PQITLWQRPVVPVKVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Ngo-Giang-Huong, N Resistance patterns selected by nevirapine vs. efavirenz in HIV-infected patients failing first-line antiretroviral treatment: A bayesian analysis. PLoS ONE, 2011