<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
LVMP1060 LVMP1060 Cameroon 1999 HIV1 D PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, E35D, M36I, R41K, I62V, I64V  
>LVMP1060| codons 1-99
PQITLWQRPLVSIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QVLVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, K43R, K49R, V60I, I135V, S162A, K173T, Q174K, D177E, T200A, Q207E, V245Q, E248D, S251T, A272P, K281R, T286A, I293V, E297Q, Q334H, Y339W, A376S, K390R, T403M  
>LVMP1060| codons 1-421
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEREGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDTWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTEVVPLTQEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHGQWTWQIYQEPFKNLKTGKYARMRGA
HTNDVKQLTEAVQKISTESIVIWGKTPKFRLPIQKETWEAWWMEYWQATWIPEWEFVNTP
P

References
Author Title Citation
Vergne, L Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: evidence of many minor drug resistance mutations in treatment-naive patients. J Clin Microbiol, 2000