<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
LVMP1035 LVMP1035 Cameroon 1998 HIV1 F PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I15V, K20R, E35D, M36I, R41K, K45R, I62V, H69Q, L89M, I93L  
>LVMP1035| codons 1-99
PQITLWQRPIVTIKVGGQLREALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYD
QVLIEICGQKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, K49R, K122E, D123E, T165I, E169D, K173A, Q174K, D177E, I178L, I202V, Q207E, P243T, V245Q, D250S, A272P, K275R, K277R, Q278H, T286A, E291D, V292I, I293V, E297A, L303M, D324E, I329V, Q334H, G335D, F346H, R356K, M357R, G359S, A371V, S379G, T386V, K390R, A400T, V417I  
>LVMP1035| codons 1-417
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILDPFRAKNPELVI
YQYMDDLYVGSDLEIGQHRTKVEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQTIQLPEKSSWTVNDIQKLVGKLNWASQIYPGIRVRHLCKLLRGAKALTDIVPLTAEAE
LEMAENREILKEPVHGVYYDPSKELIAEVQKQGHDQWTYQIYQEPHKNLKTGKYAKRRSA
HTNDVKQLTEVVQKIATEGIVIWGKVPKFRLPIQKETWETWWTEYWQATWIPEWEFI

References
Author Title Citation
Vergne, L Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: evidence of many minor drug resistance mutations in treatment-naive patients. J Clin Microbiol, 2000