Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| LVMP1035 | LVMP1035 | Cameroon | 1998 | HIV1 | F | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I15V, K20R, E35D, M36I, R41K, K45R, I62V, H69Q, L89M, I93L |
| >LVMP1035| codons 1-99 PQITLWQRPIVTIKVGGQLREALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYD QVLIEICGQKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, K49R, K122E, D123E, T165I, E169D, K173A, Q174K, D177E, I178L, I202V, Q207E, P243T, V245Q, D250S, A272P, K275R, K277R, Q278H, T286A, E291D, V292I, I293V, E297A, L303M, D324E, I329V, Q334H, G335D, F346H, R356K, M357R, G359S, A371V, S379G, T386V, K390R, A400T, V417I |
| >LVMP1035| codons 1-417 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILDPFRAKNPELVI YQYMDDLYVGSDLEIGQHRTKVEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQTIQLPEKSSWTVNDIQKLVGKLNWASQIYPGIRVRHLCKLLRGAKALTDIVPLTAEAE LEMAENREILKEPVHGVYYDPSKELIAEVQKQGHDQWTYQIYQEPHKNLKTGKYAKRRSA HTNDVKQLTEVVQKIATEGIVIWGKVPKFRLPIQKETWETWWTEYWQATWIPEWEFI |
References
| Author | Title | Citation |
| Vergne, L | Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: evidence of many minor drug resistance mutations in treatment-naive patients. | J Clin Microbiol, 2000 |