<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
LVMP798 LVMP798 Cameroon 1997 HIV1 F PBMC None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, K20R, E34K, E35D, M36I, P39Q, R41K, Q61E, L63P, H69Q, L89M  
>LVMP798| codons 1-99
PQITLWQRPLVTIKVGGQLREALLDTGADDTVLKDINLQGKWKPKMIGGIGGFIKVRQYD
EIPIEICGQKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E40D, K101R, D123E, T165I, K173A, Q174K, D177E, E194A, T200A, Q207E, P243A, V245Q, E248D, D250S, A272P, Q278H, T286A, E291D, I293V, E297A, L303M, I329V, Q334H, G335D, F346H, M357R, G359S, A371V, S379G, T386V, K390R, A400T  
>LVMP798| codons 1-421
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLRKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRAKNPEIVI
YQYMDDLYVGSDLAIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQAIQLPDKSSWTVNDIQKLVGKLNWASQIYPGIKVKHLCKLLRGAKALTDVVPLTAEAE
LEMAENREILKEPVHGVYYDPSKDLIAEVQKQGHDQWTYQIYQEPHKNLKTGKYARRRSA
HTNDVKQLTEVVQKIATEGIVIWGKVPKFRLPIQKETWETWWTEYWQATWIPEWEFVNTP
P

References
Author Title Citation
Vergne, L Genetic diversity of protease and reverse transcriptase sequences in non-subtype-B human immunodeficiency virus type 1 strains: evidence of many minor drug resistance mutations in treatment-naive patients. J Clin Microbiol, 2000