<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12E, K14E, I15V, E35N, M36I, R41K, R57K, Q61N, I62V, L63P, T74S, L89M E65R
>BR2018| codons 1-99
PQITLWQRPLVEIEVGGQLKEALLDTGADDTVLENINLPGKWKPKMIGGIGGFIKVKQYD
NVPIRICGHKAIGSVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N   D123E, I135M, K166R, V189I, T200A, A272P, K281R, P294T, E297K, V317A, Q334N, Y342F, M357T, A376S, T377I, K390R, T397I, A400T, V435I, D460H, R461K, T470S, H483L, I506L, L517I, K527R, A554T  
>BR2018| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDIVI
YQYVDDLYIGSDLEIGQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTEVITLTKEAE
LELAENREILKEPVHGAYYDPSKDLIAEIQKQGNGQWTYQIFQEPFKNLKTGKYARTRGA
HTNDVKQLTEAVQKISIESIVIWGKTPKFRLPIQKEIWETWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIIGAETFYVDGAANRETKLGKAGYVTHKGRQKVVSLSDTTNQKTELQ
AILLALQDSGLEVNIVTDSQYALGILQAQPDKSESEIVSQIIEQLIRKEKVYLAWVPAHK
GIGGNEQVDKLVSTGIRKVL

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, S24N, L28I, S39C, I72V, K103Q, S119P, I135V, Q137R, F181L, V201I, A205S, K211R, Q216H, D256E S283G
>BR2018| codons 1-288
FLDGIDKAQEDHEKYHSNWRAMANDFNIPPVVAKEIVACCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLQLAGRWPVKTIHTDNGPN
FTSTTVKAACWWAGVKREFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
LIHNFKRKGGIGGYSAGERIIDIISTDIQTRELQKHITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSEIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

References
Author Title Citation
Sanabani, SS Characterization of partial and near full-length genomes of HIV-1 strains sampled from recently infected individuals in Sao Paulo, Brazil. PLoS ONE, 2011