<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    D6E, S17N, I72V, T112I, T124N, T125V, G163Q, A205S  
>BR1046| codons 1-288
FLDGIEKAQEEHEKYHNNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKIIHTDNGSN
FTSNVVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIQQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIISTDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    R41K, I62T, L63P, H69Y, A71T  
>BR1046| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD
QTPIEICGYKTIGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K64R, K103R, K122E, N175H, T200A, Q207E, F214L, V245E, K277R, A288S, I293V, Q334E, M357T, V365I, K390R, E396D, A400T, T403S, F440Y, E449D, V467I, L491P, S519N, K527N, V531I, A554S  
>BR1046| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIRKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQHPDIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKSLTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGEGQWTYQIYQEPFKNLKTGKYARTRGA
HTNDIKQLTEAVQKIATESIVIWGKTPKFRLPIQKDTWETWWSEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIVGAETYYVDGAANRDTKLGKAGYVTDRGRQKVISLTDTTNQKTELQ
AIHLALQDSGPEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLINKEKIYLAWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Sanabani, SS Characterization of partial and near full-length genomes of HIV-1 strains sampled from recently infected individuals in Sao Paulo, Brazil. PLoS ONE, 2011