<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, E35D, N37K, R41N, L63P, H69K, T74A, V77I, L89M, I93L  
>BR2022| codons 1-99
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEDMKLPGNWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGAVLIGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39G, S48T, K101R, K122E, K173A, D177E, Q207G, R211K, V245Q, A272P, K277R, E291D, V292I, I293V, P294T, D324P, G335S, P345T, R356K, G359T, T369A, T377V, K390R, E404D, V435A, G436E, N447S, L452M, V466I, S468T, D471E, H483Q, L491P, S519N, K530R, A534S, A554N  
>BR2022| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICGEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLRKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI
YQYMDDLYVGSDLEIGQHRTKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPSKPLIAEIQKQGQSQWTYQIYQETFKNLKTGKYAKMRTA
HTNDVKQLAEAVQKIAVESIVIWGKTPKFRLPIQKETWEAWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIAEAETFYVDGAASRETKMGKAGYVTDRGRQKIVTLTETTNQKTELQ
AIQLALQDSGPEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLSWVPAHK
GIGGNEQVDKLVSNGIRKVL

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, K14R, S24N, D25E, V31I, M50I, L101I, T112V, S119G, T124N, K136Q, V201I, K211R, T218I, L234I, I251L, A265V, R269K, D278A  
>BR2022| codons 1-288
FLDGIDKAQEDHERYHSNWRAMANEFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI
WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGGN
FTSNTVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTRELQKQIIKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVLQDNSDIKVVPRRKVKIIKDYGKQMAGADCVASRQDED

References
Author Title Citation
Sanabani, SS Characterization of partial and near full-length genomes of HIV-1 strains sampled from recently infected individuals in Sao Paulo, Brazil. PLoS ONE, 2011