<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    D6N, K7Q, S17N, V32I, I72V, L74I, S119P, T124N, T125A, S153A, V176L, T218I, K219N, I220L, N222K, N254S, S255G  
>BR1013| codons 1-288
FLDGINQAQEEHEKYHNNWRAMASDFNLPPVIAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVIIVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGPN
FTSNAVKAACWWAGIKQEFGIPYNPQSQGVVEAMNKELKKIIGQVRDQAEHLKTALQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQIINLQKFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDSGDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, T12I, N37T, R41K, I62V, L63P, C67S, I72V, V77I  
>BR1013| codons 1-99
PQITLWQRPVVIIKIGGQLKEALLDTGADDTVLEEMTLPGKWKPKMIGGIGGFIKVRQYD
QVPIEISGHKAVGTVLIGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        I50V, V60I, S68G, K122E, I135T, I178L, Q197L, Q207D, A272P, K277R, A288S, I293V, E297A, P313Q, S322A, G333E, Q334R, F346L, I375V, T386I, K390R, T403M, R461K, S468P, A554T  
>BR1013| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKVGPENPYNTPI
FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDLVI
YQYMDDLYVGSDLEIGLHRTKIEELRDHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKSLTEVVPLTAEAE
LELAENREILKEQVHGVYYDPAKDLIAEIQKQERGQWTYQIYQEPLKNLKTGKYARMRGA
HTNDVKQLTEAVQKVATESIVIWGKIPKFRLPIQKETWEAWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTDKGRQKVVPLTDTTNQKTELQ
AIHLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHK
GIGGNEQVDKLVSTGIRKVL

References
Author Title Citation
Sanabani, SS Characterization of partial and near full-length genomes of HIV-1 strains sampled from recently infected individuals in Sao Paulo, Brazil. PLoS ONE, 2011