<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, L19I, K20I, M36I, N37D, K43R, L63P, I64IM, H69K, L89M E35S
>SK4003-M18| codons 1-99
PQITLWQRPLVTVKIGGQIIEALLDTGADDTVLESIDLPGRWRPKMIGGIGGFIKVRQYD
QIPMEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184MV   K103N   K20R, V35T, T39L, V60I, K122E, I135V, S162A, K173I, Q174K, D177E, I178M, T200A, Q207A, R211K, L228LP, V245Q, A272P, K281R, T286A, E291D, I293V, E312D, V317A  
>SK4003-M18| codons 1-320
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICLEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRIKNPEMVI
YQYVDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTPDKKHQKEPPFPWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDVVPLTEEAE
LELAENREILKDPVHGAYYD

References
Author Title Citation
Aghokeng, AF High failure rate of the ViroSeq HIV-1 genotyping system for drug resistance testing in Cameroon, a country with broad HIV-1 genetic diversity J Clin Microbiol, 2011