<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65KR, M184MV   K103N, Y181C   V35KR, T39TA, V60I, K122E, D123NS, I135IT, I142IT, K173A, Q174K, T200A, Q207A, F214L, H221Y, L228LH, V245Q, E248D, D250E, A272P, K275KQ, V276T, K281R, L283I, E291D, V292VI, I293V, R307K, E312N  
>SK6031-M18| codons 1-320
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALREICAEMEKEGKISKIGPENPYNTPI
FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGTRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPDIVI
CQYVDDLYVGSDLEIGQHRAKIEELRAHLLRWGLTTPDKKYQKEPPFHWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIQTKQLCRLIRGTKALTDIVPLTEEAE
LELAENKEILKNPVHGVYYD

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, T12A, L19I, E35D, M36I, R41K, I62V, L63T, C67D, H69R, L89M  
>SK6031-M18| codons 1-99
PQITLWQRPIVAIKIGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QVTIEIDGRKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Aghokeng, AF High failure rate of the ViroSeq HIV-1 genotyping system for drug resistance testing in Cameroon, a country with broad HIV-1 genetic diversity J Clin Microbiol, 2011