<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74LV, M184MIV   K103N, Y181C   V35T, T39N, E40D, K49R, V60VI, K104R, K122E, D123E, T165IL, K173T, Q174K, D177E, I178IM, T200A, Q207DN, R211K, H221Y, V245N, A272AS, K281R, E291D, V292I, I293V, E297EA, E312N, Q334E  
>CP 001 1781| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNDMEKEGKISRIGPENPYNTPI
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKNRSVTVLDVGDAYFSVPL
DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMLKILEPFRTKNPEMVI
CQYVDDLYVGSDLEIGQHRAKIEELRNHLLKWGFTTPDKKYQKEPPFLWMGYELHPDKWT
VQPINLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCRLLRGTKALTDIVPLTAEAE
LELAENREILKNPVHGVYYDPSKDLIAEIQKQGE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, I15V, L19I, K20I, E35D, M36I, N37D, R57RK, L63P, I64IL, C67S, H69K, K70R, V82I, L89M  
>CP 001 1781| codons 1-99
PQITLWQRPLVTVKVGGQIIEALLDTGADDTVLEDIDLPGRWKPKMIGGIGGFIKVKQYD
QIPLEISGKRAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Charpentier, C Virological response and resistance profiles after 18 to 30 months of first- or second-/third-line antiretroviral treatment: A cross-sectional evaluation in HIV type 1-infected children living in the Central African Republic. ARHR, 2011