<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V F77FL Y181C   V35T, E40D, K49KR, F87FL, K101KR, K122KE, D123NT, Q174QK, P176PT, V179VI, G196E, T200A, Q207E, L228LR, D237E, V245K, A272P, I274IV, K275R, Q278HY, K281R, E291D, V292I, I293V, E297EK, I329IV V60VA, V90VA
>CP 001 040| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKISRIGPENPYNTPA
FAIKKKDSTKWRKLVDLRELNKRTQDLWEAQLGIPHPAGLRKKKSVTVLDVGDAYFSVPL
DETFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKKNTDIII
CQYVDDLYVGSDLEIEQHRAKIEELREHLLRWGFTTPDKKHQKEPPFRWMGYELHPEKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGVRVKYLCRLLRGTKALTDIVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, T12A, I13V, K14R, I15AV, G16A, E35D, M36I, N37D, D60E, Q61N, L63T, C67E, H69K, V77I, L89M  
>CP 001 040| codons 1-99
PQITLWQRPVVAVRVAGQLKEALLDTGADDTVLEDIDLPGRWKPKMIGGIGGFIKVRQYE
NITIEIEGKKAIGTVLIGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Charpentier, C Virological response and resistance profiles after 18 to 30 months of first- or second-/third-line antiretroviral treatment: A cross-sectional evaluation in HIV type 1-infected children living in the Central African Republic. ARHR, 2011