Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 194 | CP 001 026 | Central African Republic | 2010 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K101KE, K103N | K238KT | E6EK, K11T, E28EK, V35T, T39D, V90VI, D121H, K122E, I135IM, S162F, K173S, Q174K, D177E, G196E, Q207A, V245Q, A272P, T286A, E291ED, E297D, P321PS, D324E | T165Q |
| >CP 001 026| codons 1-333 PISPIKTVPVTLKPGMDGPKVKQWPLTKEKIKALTEICDEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLEKNKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQFSMQKILEPFRSKNPEIVI YQYVDDLYVGSDLEIEQHRTKIEELRAHLLRWGFTTPDKKHQKEPPFLWMGYELHPDTWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDVIPLTDEAE LELAENREILKEPVHGVYYDSSKELIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, K14NS, G16E, E35D, M36I, R41K, L63T, H69K, L89M |
| >CP 001 026| codons 1-99 PQITLWQRPVVTVSIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QITIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Charpentier, C | Virological response and resistance profiles after 18 to 30 months of first- or second-/third-line antiretroviral treatment: A cross-sectional evaluation in HIV type 1-infected children living in the Central African Republic. | ARHR, 2011 |