<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K101KE, K103N K238KT E6EK, K11T, E28EK, V35T, T39D, V90VI, D121H, K122E, I135IM, S162F, K173S, Q174K, D177E, G196E, Q207A, V245Q, A272P, T286A, E291ED, E297D, P321PS, D324E T165Q
>CP 001 026| codons 1-333
PISPIKTVPVTLKPGMDGPKVKQWPLTKEKIKALTEICDEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLEKNKSVTVLDVGDAYFSVPL
HEDFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQFSMQKILEPFRSKNPEIVI
YQYVDDLYVGSDLEIEQHRTKIEELRAHLLRWGFTTPDKKHQKEPPFLWMGYELHPDTWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDVIPLTDEAE
LELAENREILKEPVHGVYYDSSKELIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, K14NS, G16E, E35D, M36I, R41K, L63T, H69K, L89M  
>CP 001 026| codons 1-99
PQITLWQRPVVTVSIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QITIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Charpentier, C Virological response and resistance profiles after 18 to 30 months of first- or second-/third-line antiretroviral treatment: A cross-sectional evaluation in HIV type 1-infected children living in the Central African Republic. ARHR, 2011