<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, E35D, M36I, R41K, L63T, I66IM, H69K, P79PH, L89M W42WR
>CP 001 227| codons 1-99
PQITLWQRPIVTVKIGGQLKEALLDTGADDTVLEDINLPGKRKPKMIGGIGGFIKVRQYD
QITIEMCGKKAIGTVLVGHTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N, M230L V108VI, P225PH E6D, K11T, K20KR, E28EK, V35T, T39K, K43E, K122E, D123N, K166KR, E169EG, F171Y, K173A, Q174K, D177E, T200A, Q207A, R211S, H221HY, K238KR, V245E, A272P, K275KQ, K277R, T286A, A288G, E291D, V292I, I293V, P294V, E312N S268SI, L282LF, T296TI
>CP 001 227| codons 1-334
PISPIDTVPVTLKPGMDGPRVKQWPLTKEKIKALTEICKEMEEEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILGPYRAKNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTPDKKYQKEHPFLWLGYELHPDRWT
VQPIELPEKDSWTVNDIQKLVGKLNWAIQIYPGIQVRQLCKFLRGAKGLTDIVVLIEEAE
LELAENREILKNPVHGVYYDPSKDLIAEIQKQGQ

References
Author Title Citation
Charpentier, C Virological response and resistance profiles after 18 to 30 months of first- or second-/third-line antiretroviral treatment: A cross-sectional evaluation in HIV type 1-infected children living in the Central African Republic. ARHR, 2011