<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K101E, G190A A98G V35T, T39N, E40D, V60I, K104R, K122E, D123N, I135V, I142V, K173T, D177E, T200A, Q207A, R211K, D237DE, V245Q, E248N, A272P, K281R, E291D, V292I, I293V, E297A, E312N, V317A, P321S, D324E, I329V, Q334E  
>CP 001 949| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNDMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLEKKRSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPEIVI
YQYVDDLYVASDLEIGQHRAKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPEKWT
VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTDIVPLTAEAE
LELAENREILKNPVHGAYYDSSKELIAEVQKQGE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12N, I13V, I15V, L19I, K20I, E35D, M36I, R41K, L63P, C67S, H69K, K70KR, V75I, V82I, L89M  
>CP 001 949| codons 1-99
PQITLWQRPLVNVKVGGQIIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEISGKRAIGTILVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Charpentier, C Virological response and resistance profiles after 18 to 30 months of first- or second-/third-line antiretroviral treatment: A cross-sectional evaluation in HIV type 1-infected children living in the Central African Republic. ARHR, 2011