<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V T215TI Y181C V108VI K20KR, I31IL, V35T, T39L, K49KR, T69TN, I135IT, T139TR, K173T, Q174K, Q207D, R211K, F214FL, H221HY, F227FS, T240TK, P243S, V245Q, D250E, A272P, V276IT, E291D, V292VI, I293V, E297T, V317VA, D324E, L325I  
>CP 001 2096| codons 1-334
PISPIETVPVKLKPGMDGPRVKQWPLTEEKLKALTEICLEMEKEGKISRIGPENPYNTPV
FAIKKKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYFSVPL
DKDFRKYTAFTIPSTNNERPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPDIVI
CQYVDDLYVGSDLEIGQHRTKIEELRDHLLKWGLITPDKKYQKEPPSLWMGYELHPDKWK
VQSIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKTKQLCKLLRGTKALTDIVPLTTEAE
LELAENREILKEPVHGAYYDPSKEIIAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, I15V, K20I, E35D, M36I, R41K, R57K, L63PS, I64M, L89M  
>CP 001 2096| codons 1-99
PQITLWQRPLVTVKVGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QISMEICGHKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Charpentier, C Virological response and resistance profiles after 18 to 30 months of first- or second-/third-line antiretroviral treatment: A cross-sectional evaluation in HIV type 1-infected children living in the Central African Republic. ARHR, 2011