<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   Y181C   P4S, V8I, V35T, E40D, K102Q, V118I, I135V, K173A, Q174K, D177EK, V179I, T200A, Q207E, R211K, F214L, L228R, V245Q, A272P, K281R, T286A, E291A, V292I, I293V, L295M, E297V, L301M, I329L F227FV
>CP 001 381| codons 1-334
PISSIETIPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSIPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPKIII
CQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPVRWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTAIVPMTVEAE
MELAENREILKEPVHGVYYDPSKDLIAELQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, G17E, L19S, K20I, E35D, M36I, R41K, I62V, L63R, I64M, H69K, L89M K14K*
>CP 001 381| codons 1-99
PQITLWQRPLVTV*IGEQSIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QVRMEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Charpentier, C Virological response and resistance profiles after 18 to 30 months of first- or second-/third-line antiretroviral treatment: A cross-sectional evaluation in HIV type 1-infected children living in the Central African Republic. ARHR, 2011