<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
      V179D K11T, V35T, T39N, K102KR, K103KR, D121H, K122E, D123GS, I135M, S162H, K173IL, Q174K, D177G, G196E, Q197QE, E203D, Q207N, R211K, V245Q, D250E, A272S, T286A, I293V, E297K, E312D, H315Y, D324DE, E328D  
>CP 001 899| codons 1-333
PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALTEICNEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRRKSVTVLDVGDAYFSVPL
HESFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQHSMTKILEPFRLKNPGIDI
YQYMDDLYVGSDLEIEEHRTKIDELRNHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGAKALTEVVPLTKEAE
LELAENREILKDPVYGVYYDPSKELIADIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10LI, T12TAS, I13V, K14KR, I15IV, E35D, M36I, N37NT, R41RK, I62V, L63T, I64M, H69K, K70KR, L89M  
>CP 001 899| codons 1-99
PQITLWQRPIVSVRVGGQLKEALLDTGADDTVLEDITLPGKWKPKMIGGIGGFIKVRQYD
QVTMEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Charpentier, C Virological response and resistance profiles after 18 to 30 months of first- or second-/third-line antiretroviral treatment: A cross-sectional evaluation in HIV type 1-infected children living in the Central African Republic. ARHR, 2011