<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
37 CP0012457 Central African Republic 2010 HIV1 CRF25_cpx Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E28A, V35T, T39N, E40D, V60I, K104KR, D123E, I135T, K173A, Q174K, D177E, V179I, T200A, Q207A, R211K, V245Q, D250E, S251D, A272P, K281R, L283I, V292I, I293V, E297T D113DG
>CP0012457| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTAEKIKALTEICNDMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGGAYFSVPL
DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIII
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKEDWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLIRGTKALTEIVPLTTEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12N, I13V, I15IV, L19IT, K20I, E35Q, M36I, N37D, L63P, C67S, H69K, K70KR, V82I, L89M  
>CP0012457| codons 1-99
PQITLWQRPLVNVKVGGQTIEALLDTGADDTVLEQIDLPGRWKPKMIGGIGGFIKVRQYD
QIPIEISGKRAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Charpentier, C Virological response and resistance profiles after 18 to 30 months of first- or second-/third-line antiretroviral treatment: A cross-sectional evaluation in HIV type 1-infected children living in the Central African Republic. ARHR, 2011