<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V V75I Y181C   K11T, P14PT, I31IL, V35T, T39N, V90VI, K104KN, D121H, K122E, D123S, I132L, I135T, S162C, K173S, Q174K, D177E, G196E, T200A, Q207A, R211K, H221HY, V245Q, A272AP, T286A, E291D, I293IV, E297K  
>CP 001 2052| codons 1-334
PISPIETVPVTLKTGMDGPKVKQWPLTEEKLKALTEICNEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLIDFRELNKRTQDFWEIQLGIPHPAGLKKKNSVTVLDVGDAYFSVPL
HESFRKYTAFTLPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRSKNPEIVI
CQYVDDLYVGSDLEIEQHRAKIEELRAHLLKWGFTTPDKKYQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDVVPLTKEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  V11I L10I, I13V, K20R, M36I, L63T, I64L, H69K, L89M  
>CP 001 2052| codons 1-99
PQITLWQRPIITVKIGGQLREALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYD
QITLEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Charpentier, C Virological response and resistance profiles after 18 to 30 months of first- or second-/third-line antiretroviral treatment: A cross-sectional evaluation in HIV type 1-infected children living in the Central African Republic. ARHR, 2011