<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 Unknown NA
2 3TC+D4T+LPV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10LI, K14KR, E35D, M36I, R41K, I62IV, L63AV, I64IL, H69K, K70KR, I72IV, L89M  
>CP 001-259| codons 1-99
PQITLWQRPIVTIRIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QVVLEICGKRAVGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103KN, Y188Y*FL V179VD K11T, K20R, V35T, T39TKN, K102KR, D121H, K122E, I135M, I142V, S162H, K173ST, Q174K, D177E, G196E, T200I, Q207A, R211S, P243S, V245Q, A272P, K281R, T286A, E291D, I293V  
>CP 001-259| codons 1-333
PISPIETVPVTLKPGMDGPRVKQWPLTEEKIKALTEICNEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRNKSVTVLDVGDAYFSVPL
HEDFRKYTAFTIPSMNNETPGVRYQYNVLPQGWKGSPAIFQHSMTKILEPFRTKNPEIDI
YQYVDDLLVGSDLEIEQHRIKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQSIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

References
Author Title Citation
Charpentier, C Virological response and resistance profiles after 18 to 30 months of first- or second-/third-line antiretroviral treatment: A cross-sectional evaluation in HIV type 1-infected children living in the Central African Republic. ARHR, 2011