Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 4 | CP 001-045 | Central African Republic | 2010 | HIV1 | CRF01_AE | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | NA |
| 2 | 3TC+AZT+IDV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | L33I | L10V, I13V, L19F, K20T, E35D, M36I, R41K, R57K, L63P, H69K, T74S, L89I |
| >CP 001-045| codons 1-99 PQITLWQRPVVTVKIGGQFTEALLDTGADDTVIEDINLPGKWKPKMIGGIGGFIKVKQYD QIPIEICGKKAIGSVLVGPTPVNIIGRNIMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184MV, T215Y | V75I | Y181C | V8I, K11T, V35T, T39KR, K43E, T69S, K101R, D121H, K122E, D123S, I132L, K173A, Q174K, V179I, E194D, G196GE, Q207A, R211S, H221Y, V245E, R284RK, T286A, A288T, E291D, V292I, I293V, P294T, E312T, I326V |
| >CP 001-045| codons 1-334 PISPIETIPVTLKPGMDGPKVKQWPLTEEKIKALTEICRELEEEGKISKIGPENPYNTPV FAIKKKDSSKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLRKKKSVTVLDVGDAYFSVPL HESFRKYTAFTLPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPDIII CQYVDDLYVGSDLDIEQHRTKIEELRAHLLSWGFYTPDKKYQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLKGAKTLTDIVTLTEEAE LELAENREILKTPVHGVYYDPSKDLVAEIQKQGQ |
References
| Author | Title | Citation |
| Charpentier, C | Virological response and resistance profiles after 18 to 30 months of first- or second-/third-line antiretroviral treatment: A cross-sectional evaluation in HIV type 1-infected children living in the Central African Republic. | ARHR, 2011 |