<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 Unknown NA
2 D4T+DDI+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, T215Y M184L, K219Q Y188L, M230L   K11T, V35KR, T39D, V106L, L109I, D121H, K122E, D123S, S134SN, A158S, K173S, Q174K, D177E, V179I, G196E, T200A, I202V, Q207A, R211S, F227Y, V245Q, T286TA, A288AS, I293V, P294T, E312D, D324E  
>CP 001-039| codons 1-333
PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALREICDELEKEGKISKIGPENPYNTPV
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSLTVIDVGDAYFSVPL
HESFRKYTAFTIPNINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRSKNPEIII
YQYLDDLLVGSDLEIEQHRAKVEELRAHLLSWGFYTPDQKHQKEPPYLWLGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKSLTEVVTLTEEAE
LELAENREILKDPVHGVYYDPSKELIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V82F, L90M   L10I, I13V, G16E, K20I, E35N, M36I, P39Q, R41K, R57RK, I62V, L63T, I64IL, H69K, I72T, T74S, L89M  
>CP 001-039| codons 1-99
PQITLWQRPIVTVKIEGQLIEALLDTGADDTVLENINLQGKWKPKMIGGIGGFIKVKQYD
QVTLEICGKKATGSVLVGPTPFNIIGRNMMTQIGCTLNF

References
Author Title Citation
Charpentier, C Virological response and resistance profiles after 18 to 30 months of first- or second-/third-line antiretroviral treatment: A cross-sectional evaluation in HIV type 1-infected children living in the Central African Republic. ARHR, 2011