Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CB-1 | CB-1 | Italy | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDC | 43 |
| 2 | 3TC+AZT | 17 |
| 3 | 3TC+D4T+IDV | 47 |
| 4 | 3TC+D4T+RTV+SQV | 30 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M, M184V | A62V, V75I, F77L, F116Y, K219Q | E40K, K43N, E53D, S68G, T107TP, V118I, D121H, K122E, I178L, T200A, I202V, R211T, F214L | W24WG, I50IF |
| >CB-1| codons 1-242 PISPIETVPVKLKPGMDGPKVKQGPLTEEKIKALVEICTKMENEGKISKFGPDNPYNTPV FVIKKKDGTKWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKKKSVPVLDVGDAYYSIPL HEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKQNPDLVI YQYVDDLYVGSDLEIGQHRAKVEELRQHLLTWGLTTPDQKHQKEPPFLWMGYELHPDKWT VQ |
References
| Author | Title | Citation |
| Balotta, C | Prevalence of multiple dideoxynucleoside analogue resistance (MddNR) in a multicenter cohort of HIV-1 infected Italian patients with virologic failure. | JAIDS, 2000 |
| Gonzales, MJ | Extended spectrum of HIV-1 reverse transcriptase mutations in patients receiving multiple nucleoside analog inhibitors. | AIDS, 2003 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |