Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CB-267 | CB-267 | Italy | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT| 3TC| DDI| D4T| IDV| NFV| SQV| DLV| NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L63A, H69N, V77I, N83NH, I93IM |
| >CB-267| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QIAIEICGNKAIGTVLIGPTPVHIIGRNLLTQMGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67NT, K70R, M184V | K219Q | K103N | K49R, I50V, V60I, T69TI, I94IL, T107TP, D123E, S162DN, D177E, I180V, T200E, R211K |
| >CB-267| codons 1-253 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISRVGPENPYNTPI FAIKKKTSIRWRKLVDFRELNKRTQDFWEVQLGLPHPAGLKKNKSVPVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRKQNPEIVV YQYVDDLYVGSDLEIGQHREKIEELRQHLLKWGFTTPDQKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWT |
References
| Author | Title | Citation |
| Balotta, C | Prevalence of multiple dideoxynucleoside analogue resistance (MddNR) in a multicenter cohort of HIV-1 infected Italian patients with virologic failure. | JAIDS, 2000 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |