<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    D3E, K7KQ, R20K, I72V, L74I, S81SR, T112V, I113V, S119P, T124S, T125A, G134N, K136H, D167E, V201I, T218I, L234I, S255N W132WG
>RU_915_1035| codons 1-288
FLEGIDQAQEEHEKYHSNWKAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVIIVAVHVARGYIEAEVIPAETGQETAYFLLKLAGRWPVKVVHTDNGPN
FTSSAVKAACWGANIHQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNNDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, K14R, E35D, M36I, R41K, L63P, H69K, L89M, I93L  
>RU_915_1035| codons 1-99
PQITLWQRPIVTIRIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K11AT, V35T, T39R, K122E, D123S, S162A, K173S, Q174K, D177E, E194K, Q207A, R211S, V245M, E248D, A272P, T286A, E291D, V292I, I293V, P294T, V317A, I326V, G335D, R356K, M357K, R358G, G359S, E370A, A371V, I375V, K390R, T403M, L452I, D471E, Q480H, L491S, K512R, E516EK, L517I, S519N, Q520K, Q524K, K527E, A534S, A554N, K558R  
>RU_915_1035| codons 1-560
PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALTEICREMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRSKNPEIVI
YQYMDDLYVGSDLKIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIMLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGAYYDPSKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKGSA
HTNDVKQLTAVVQKVATESIVIWGKTPKFRLPIQKETWEAWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIVGAETFYVDGAANRETKIGKAGYVTDRGRQKVVSLTETTNQKTELH
AIHLALQDSGSEVNIVTDSQYALGIIQAQPDRSESKIVNKIIEKLIEKEKVYLSWVPAHK
GIGGNEQVDKLVSNGIRRVL

References
Author Title Citation
Fernandez-Garcia, A The analysis of near full-length genome sequences of HIV-1 subtype A viruses from Russia supports the monophyly of major intrasubtype clusters. ARHR, 2012