<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    D3E, R20K, D41N, I72V, L74I, T112V, S119P, T124S, T125A, G134D, K136Q, D167E, V201I, T218I, L234I, S255N  
>RU_560_1125| codons 1-288
FLEGIDKAQEEHEKYHSNWKAMASDFNLPPVVAKEIVASCNKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVIIVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKVIHTDNGPN
FTSSAVKAACWWADIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQIIKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNNDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, E35D, M36I, R41K, H69K, K70Q, V77I, L89M, I93L  
>RU_560_1125| codons 1-99
PQITLWQRPLVTVRIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKQAIGTVLIGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
  A62V     K11T, V35I, E36D, T39K, K82KR, K122E, D123S, I135T, A158S, K173L, Q174K, D177E, Q207A, R211S, V245T, E248D, A272P, K277R, T286A, E291D, V292I, I293V, P294T, I326V, G335D, R356K, M357K, R358G, G359S, E370A, A371V, I375V, V381I, K390R, T397V, T403M, L452K, S468P, D471E, Q480H, L491S, K512R, L517I, S519N, Q520K, Q524K, K527E, K530R, A534S, A554Y, K558R  
>RU_560_1125| codons 1-560
PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALIDICKEMEKEGKISKIGPENPYNTPV
FVIKKKDSTKWRKLVDFRELNRRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRLKNPEIVI
YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPITLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPSKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKGSA
HTNDVKQLTAVVQKVATESIIIWGKTPKFRLPIQKEVWEAWWMEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIVGAETFYVDGAANRETKKGKAGYVTDRGRQKVVPLTETTNQKTELH
AIHLALQDSGSEVNIVTDSQYALGIIQAQPDRSESEIVNKIIEKLIEKERVYLSWVPAHK
GIGGNEQVDKLVSYGIRRVL

References
Author Title Citation
Fernandez-Garcia, A The analysis of near full-length genome sequences of HIV-1 subtype A viruses from Russia supports the monophyly of major intrasubtype clusters. ARHR, 2012