<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+RTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32VI, M46MI, I47IATV, I54IV, V82VA   L10I, M36I, R41K, I62V, I64V, H69Y, A71T, I93L  
>60784| codons 1-99
PQITLWQRPIVTIKIGGQLKEALLDTGADDTILEEINLPGKWKPKIVGGIGGFVKVRQYD
QVLVEICGYKTIGTVLVGPTPANIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T215Y       T39A, K122P, T139TA, I142V, S162H, T200I, Q207T, R211K, V245M, K277R, Q278E, V292I, I293V, E297R, L301I  
>60784| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DPDFRKYTAFTIPSINNEAPGVRYQYNVLPQGWKGSPAIFQHSMTKILEPFRKQNPDIVI
YQYMDDLYVGSDLEIGQHRIKIEELRTHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRELCKLLRGTKALTEIVPLTREAE
IELAENREILKEPVHGVYYDPSKDLIAEIQKQGQG

References
Author Title Citation
Barber, TJ Frequency and patterns of protease gene resistance mutations in HIV-infected patients treated with lopinavir/ritonavir as their first protease inhibitor. J Antimicrob Chemother, 2012