<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+RTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V82A L10F I15V, G17D, L19I, M36I, D60E, L63P, H69K, L89M, I93L  
>56572| codons 1-99
PQITLWQRPFVTIKVGDQIKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYE
QIPIEICGKKAIGTVLVGPTPANIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       P4Q, I5V, V35T, T39E, S48T, V60I, D121H, K122E, D123S, S163T, K173A, Q174K, D177E, I178M, T200A, Q207E, R211K, V245Q, E248D, D250K, S251D, A272P, K277R, T286A, E291D, V292I, I293V, Q334N, G335D  
>56572| codons 1-341
PISQVETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
HESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSTMTKILEPFRAKNPEMVI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKKDWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGNDQWTYQI

References
Author Title Citation
Barber, TJ Frequency and patterns of protease gene resistance mutations in HIV-infected patients treated with lopinavir/ritonavir as their first protease inhibitor. J Antimicrob Chemother, 2012