<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+RTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  Q58E T12A, I13V, K14R, L33V, N37T, R41K, I62V, L63P, I64V, Q92E  
>76142| codons 1-99
PQITLWQRPLVAVRIGGQLKEALLDTGADDTVVEEMTLPGKWKPKMIGGIGGFIKVREYD
QVPVEICGHKAIGTVLVGPTPVNIIGRNLLTEIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L T215ADE     E40D, W88C, A98S, K122E, G196E, R211A, A272S, E297KT, P313T  
>76142| codons 1-341
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTDLEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFCEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYMDDLYVGSDLEIEQHRTKIEELRQHLLAWGFETPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGTKALTEVIPLTTEAE
LELAENREILKETVHGVYYDPSKDLIAEIQKQGQGQWTYQI

References
Author Title Citation
Barber, TJ Frequency and patterns of protease gene resistance mutations in HIV-infected patients treated with lopinavir/ritonavir as their first protease inhibitor. J Antimicrob Chemother, 2012