<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+RTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, L90LM   I13V, K14R, K20I, E35Q, M36I, N37NDEK, R41K, I62IV, L63P, C67E, H69K, A71AV, V82I, L89M, I93IM  
>68061| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEQIKLPGKWKPKMIGGIGGFVKVRQYD
QVPIEIEGKKVIGTVLVGPTPINIIGRNMMTQMGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E40ED, V60I, V118I, K122KE, D123NS, K173T, Q174K, D177E, I178M, T200A, Q207DE, L210M, R211K, F214L, P243PS, V245LM, E248D, D250E, A272P, T286A, E291D, V292I, I293V, K311KR, I329V, Q334L, G335D, F346Y, R356K, M357R, R358G, G359S, V381VI, T386V, K390R, Q394R, E399D N306ND
>68061| codons 1-399
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEMVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLMKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQSIMLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE
LELAEDREILREPVHGVYYDPSKDLIAEVQKQGLDQWTYQIYQEPYKNLKTGKYAKRGSA
HTNDVKQLTEAVQKIATESIIIWGKVPKFRLPIRKETWD

References
Author Title Citation
Barber, TJ Frequency and patterns of protease gene resistance mutations in HIV-infected patients treated with lopinavir/ritonavir as their first protease inhibitor. J Antimicrob Chemother, 2012