<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+RTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I84V   L10I, I13V, G16E, Q18QK, L19LP, K20I, E35D, M36I, N37T, P39S, R41K, I62V, H69K, K70R, T74A, L89M  
>60783| codons 1-99
PQITLWQRPIVTVKIEGKPIEALLDTGADDTVLEDITLSGKWKPKIIGGIGGFIKVRQYD
QVLIEICGKRAIGAVLVGPTPVNVIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
  A62AV     V35T, T39A, K43E, K126Q, I135V, S162A, K173IM, Q174K, D177E, I195L, T200A, I202IV, Q207E, R211K, L228LR, V245Q, A272P, K275R, K277R, L283I, T286A, E291D, V292I, I293V, P294T, R307K M16MI
>60783| codons 1-334
PISPIETVPVKLKPGIDGPKVKQWPLTEEKIKALTEICAEMEEEGKISKIGPENPYNTPV
FVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRQYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRMKNPEIVI
YQYMDDLYVGSDLELGQHRAKVEELREHLLKWGFTTPDKKHQKEPPFRWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVRQLCKLIRGAKALTDIVTLTEEAE
LELAENKEILKEPVHGVYYDPSKDLIAEIQKQGQ

References
Author Title Citation
Barber, TJ Frequency and patterns of protease gene resistance mutations in HIV-infected patients treated with lopinavir/ritonavir as their first protease inhibitor. J Antimicrob Chemother, 2012