<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 165

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70R, M184V D67G, K219Q K103KN, V106VM, Y188L A98AG K11KR, V35T, T39E, S48T, E53D, V60I, S68G, K102KE, V118VI, K122E, D123S, I135V, K173A, Q174R, D177E, G196GE, T200A, Q207E, R211K, F214L, L228H, Q242H, V245Q, A272Q, T286TA, E291D, V292I, I293V, D324E, G333E, Q334H  
>707PKE52F| codons 1-335
PISPIETVPVRLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPDNPYNTPI
FAIKKKGGTRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKENKSMTVLDVGDAYFSIPL
DESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRARNPEIVI
YQYVDDLLVGSDLEIEQHRAKIEELREHLLKWGLTTPDQKHQKEPPFHWMGYELHPDKWT
VHPIQLPEKDSWTVNDIQKLVGKLNWASQIYQGIKVKQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQEHG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, L19V, M36I, R41K, L63P, H69K, L89M, I93L  
>707PKE52F| codons 1-99
PQITLWQRPLVSIKIGGQVKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Green, TN Drug resistance and coreceptor usage in HIV type 1 subtype C-infected children initiating or failing highly active antiretroviral therapy in south Africa. ARHR, 2011