<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 213

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, L210W, T215Y V75I K103N P225H K20R, V35T, E36EA, T39E, V60I, W88C, I132L, K173A, D177E, G196T, T200A, Q207E, R211K, T240TK, V245Q, D250E, K277R, T286A, E291D, V292I, I293V, D324E  
>707PKE37F| codons 1-333
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICEELEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLIDFRELNKRTQDFCEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DKDFRKYTAFTLPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI
YQYVDDLYVGSDLEITQHRAKIEELREHLWKWGFYTPDKKHQKEHPFLWMGYELHPDKWK
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  L33F T12S, L19I, R41K, L63V, H69K, L89M  
>707PKE37F| codons 1-99
PQITLWQRPLVSIKIGGQIKEALLDTGADDTVFEEMNLPGKWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Green, TN Drug resistance and coreceptor usage in HIV type 1 subtype C-infected children initiating or failing highly active antiretroviral therapy in south Africa. ARHR, 2011