Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 707PKE35F | 707PKE35F | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | 117 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T69TADN, M184V | T215TI | K101E, Y181C, G190S | V8VA, E28K, V35T, T39E, W88WC, V118I, K122E, D123N, T165I, K166KR, K173A, Q174K, D177E, T200A, Q207E, L210LS, F214L, H221Y, V245Q, A272P, K275KQ, K281R, T286A, E291D, V292I, E297EK, Q334D |
| >707PKE35F| codons 1-335 PISPIETAPVKLKPGMDGPKVKQWPLTKEKIKALTEICEEMEKEGKISKIGPENPYNTPV FAIKKKDSNKWRKLVDFRELNKRTQDFCEVQLGIPHPAGLEKKKSVTVLDVGDAYFSIPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMIRILEPFRAKNPEIVI CQYVDDLYVSSDLEIGQHRAKIEELREHLSRWGLITPDKKYQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIQVKQLCRLLRGAKALTDIIPLTKEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGDG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, L19I, K20R, M36I, R41K, H69K, L89M, I93L |
| >707PKE35F| codons 1-99 PQITLWQRPLVSIKIGGQIREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Green, TN | Drug resistance and coreceptor usage in HIV type 1 subtype C-infected children initiating or failing highly active antiretroviral therapy in south Africa. | ARHR, 2011 |