<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 153

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V K219E V106M V179D, F227FL K20R, V35T, E36A, T39E, V60VI, K101A, K103KR, K104R, K122E, D123N, I135IMT, E138S, T165I, K173M, Q174K, T200A, I202V, Q207E, R211K, F214L, V245Q, E248D, A272P, K277R, Q278N, T286A, E291D, V292I, I293V, P313T, V317A  
>707PKE28F| codons 1-333
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICEEMEKEGKISKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLAKRRSMTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNSTPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRMKNPDIDI
YQYVDDLYVGSDLEIGQHRAKVEELREHLLKWGLTTPDEKHQKEPPLLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRNLCKLLRGAKALTDIVPLTEEAE
LELAENREILKETVHGAYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, G17D, L19I, K20R, E35D, M36I, P39Q, R41K, D60E, Q61D, L63AT, H69K, L89M, I93L  
>707PKE28F| codons 1-99
PQITLWQRPLVSIKVGDQIREALLDTGADDTVLEDINLQGKWKPKMIGGIGGFIKVRQYE
DITIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Green, TN Drug resistance and coreceptor usage in HIV type 1 subtype C-infected children initiating or failing highly active antiretroviral therapy in south Africa. ARHR, 2011