<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 127

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, T69~, K70R, Q151M   K103N, V106M   V35T, E36A, T39E, S48T, V60I, S68G, V90I, K122E, D123G, T139E, A158S, K173A, D177E, I178M, T200A, Q207A, R211K, V245E, A272P, E291D, V292I, I293V, D324E L34V
>707PKE22F| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKAVTAICEEMEKEGKITKIGPENPYNTPI
FAIKRKDG~RWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKNKSMTVLDVGDAYFSVPL
DEGFRKYTAFTIPSINNEEPGIRYQYNVLPMGWKGSPSIFQSSMTKILEPFRAQNPEMVI
YQYMDDLYVGSDLEIGQHRAKIEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, R41K, L63P, H69K, I93L  
>707PKE22F| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Green, TN Drug resistance and coreceptor usage in HIV type 1 subtype C-infected children initiating or failing highly active antiretroviral therapy in south Africa. ARHR, 2011