<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV 160

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70R, M184V   V106M, Y188C   K20KR, V35K, T39E, S48T, T58S, V60I, T69N, V118A, S162Y, K173T, Q174R, D177E, T200A, I202IV, Q207KNRS, R211Q, L228LH, V245Q, D250E, V292VI, I293V, E297K, P321S, D324E, Q334E  
>707PKE09F| codons 1-334
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALKEICEEMEKEGKITKIGPENPYNSPI
FAIKKKDSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSAPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRTRNPEIVI
YQYVDDLCVGSDLEIGQHRAKVEELRSHLLQWGFTTPDKKHQKEPPFHWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEIVPLTKEAE
LELAENREILKEPVHGVYYDSSKELIAEIQKQGE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, L19I, E35D, M36I, R41K, D60E, Q61E, L63LP, H69K, L89M, I93L  
>707PKE09F| codons 1-99
PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE
EIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Green, TN Drug resistance and coreceptor usage in HIV type 1 subtype C-infected children initiating or failing highly active antiretroviral therapy in south Africa. ARHR, 2011