Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | 19 |
| 2 | 3TC+AZT+EFV | 91 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, D67DN, V75M, M184V, T215Y | V106M, G190GA | V179VD, F227L | I31L, V35T, E36EA, T39E, V60I, A98AS, L109LI, K122E, D123S, S163SC, T165TI, K173T, Q174N, D177E, T200A, Q207A, R211K, V245T, A272P, E291D, V292I, I293V, E298EK, D324E, I326IV |
| >707PKE04F| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKLKALTAICEELEKEGKISKIGPENPYNTPI FAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIPHPSGLKKKKSMTVIDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSCMIKILEPFRTNNPEIDI YQYVDDLYVASDLEIGQHRAKIEELRAHLLKWGFYTPDKKHQKEPPLLWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTEKAE LELAENREILKEPVHGVYYDPSKELVAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19V, M36I, R41K, L63T, H69K, T74S, L89M, I93L |
| >707PKE04F| codons 1-99 PQITLWQRPLVTIKVGGQVKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QITIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Green, TN | Drug resistance and coreceptor usage in HIV type 1 subtype C-infected children initiating or failing highly active antiretroviral therapy in south Africa. | ARHR, 2011 |