Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CB-161 | CB-161 | Italy | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT| 3TC| DDC| D4T| IDV| RTV| SQV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215Y | V35I, K43N, E44D, V118I, K122Q, I178M, E203K, H208Y, R211K, K223E, L228R |
| >CB-161| codons 1-235 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTELENDGKISKIGPENPYNTPV FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DQDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMVI YQYVDDLYVGSDLEIGQHRTKIKELRQYLWKWGFYTPDKKHQEEPPFRWMGYELH |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A, I84V | L24I | L10I, E35D, M36I, I62V, L63C, I64V, A71AV, N83X |
| >CB-161| codons 1-99 PQITLWQRPIVTIKIGGQLKEALIDTGADDTVLEDINLPGRWKPKIIGGIGGFVKVRQYD QVCVEICGHKVIGTVLVGPTPAXVIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Balotta, C | Prevalence of multiple dideoxynucleoside analogue resistance (MddNR) in a multicenter cohort of HIV-1 infected Italian patients with virologic failure. | JAIDS, 2000 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |